Compound Detail
CHEMBL142811
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Basic Information
| ChEMBL ID | CHEMBL142811 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QDWDLCUCJILOGI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
511.5
MW (Da)
5.73
ALogP
3
HBA
2
HBD
40.2
PSA (Ų)
0.24
QED
2
Ro5 Violations
12
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 4.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Somatostatin receptor type 4 CHEMBL1853 | Ki | 4.15 | 4.15 | 71000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Somatostatin receptor type 4 | Ki | = | 71000.0 | nM | 4.15 | In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells us... | 9822540 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9822540 | 10.1021/jm980118e | Somatostatin receptor type 2 | 1 |
| 9822540 | 10.1021/jm980118e | Somatostatin receptor type 4 | 1 |
Data from ChEMBL 36 via Core Engine