Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL144446

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CC(O)(CO)CCOP(=O)(O)OP(=O)(O)O
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL144446
Phase Preclinical
Structure Type MOL
InChI Key FCVPEIMZQOLFMU-UHFFFAOYSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

280.1
MW (Da)
-0.65
ALogP
6
HBA
5
HBD
153.8
PSA (Ų)
0.38
QED
0
Ro5 Violations
7
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C5H14O9P2
MW 280.11
Aromatic Rings 0
Heavy Atoms 16
NP-Likeness 1.51

Activity Summary

EC50 1 meas. best 5.5

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
 EC50 5.5 5.5 3160.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Unchecked EC50 = 3160.0 nM 5.5 Effective concentration to activate gammadelta T cells 12383012

Literature References

PubMed DOI Target Context # Activities
12383012 10.1021/jm020224n Unchecked 1

Data from ChEMBL 36 via Core Engine