Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL144679

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CCC1OCC2(CCN(C)CC2)O1

Basic Information

ChEMBL ID CHEMBL144679
Phase Preclinical
Structure Type MOL
InChI Key VGEBJUNXAXJOTD-UHFFFAOYSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

185.3
MW (Da)
1.23
ALogP
3
HBA
0
HBD
21.7
PSA (Ų)
0.61
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C10H19NO2
MW 185.27
Aromatic Rings 0
Heavy Atoms 13
NP-Likeness 0.60

Activity Summary

Ki 2 meas. best 6.13

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Muscarinic acetylcholine receptor M1
CHEMBL276
Ki 6.13 6.005 745.0 2

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
- 10.1016/S0960-894X(00)80537-5 Muscarinic acetylcholine receptor M1 6
3339620 10.1021/jm00397a039 Muscarinic acetylcholine receptor 2
3339620 10.1021/jm00397a039 Unchecked 1

Data from ChEMBL 36 via Core Engine