Compound Detail
CHEMBL1467092
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Basic Information
| ChEMBL ID | CHEMBL1467092 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PPJNOGXJWIRDCZ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
337.4
MW (Da)
3.06
ALogP
7
HBA
2
HBD
93.0
PSA (Ų)
0.76
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dual specificity protein phosphatase 6 CHEMBL5511 | IC50 | 4.43 | 4.43 | 36800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dual specificity protein phosphatase 6 | IC50 | = | 36800.0 | nM | 4.43 | PUBCHEM_BIOASSAY: MKP-3 in vitro HTS assay. (Class of assay: confirmatory) [Rela... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 27289323 | 10.1016/j.bmcl.2016.05.018 | Histone-lysine N-methyltransferase EZH2 | 1 |
Data from ChEMBL 36 via Core Engine