Compound Detail
CHEMBL148103
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL148103 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QDSYELYTTVSDIP-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
382.4
MW (Da)
3.88
ALogP
4
HBA
0
HBD
53.3
PSA (Ų)
0.81
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2A CHEMBL224 | Ki | 6.82 | 6.82 | 150.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2A | Ki | = | 150.0 | nM | 6.82 | Binding affinity for displacement of [3H]ketanserin to human 5-hydroxytryptamine... | 11784153 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11784153 | 10.1021/jm011030v | 5-hydroxytryptamine receptor 2A | 2 |
| 11784153 | 10.1021/jm011030v | 5-hydroxytryptamine receptor 2C | 1 |
| 11784153 | 10.1021/jm011030v | D(2) dopamine receptor | 1 |
| 11784153 | 10.1021/jm011030v | Adrenergic receptor alpha-1 | 1 |
Data from ChEMBL 36 via Core Engine