Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL1490787

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
Cc1cccc(-c2nc(O)c3ccccc3n2)c1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL1490787
Phase Preclinical
Structure Type MOL
InChI Key HGMYBXXEFAWWSC-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
6
Publications
0
Known Names

Molecular Properties

236.3
MW (Da)
3.31
ALogP
3
HBA
1
HBD
46.0
PSA (Ų)
0.70
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C15H12N2O
MW 236.27
Aromatic Rings 3
Heavy Atoms 18
NP-Likeness -1.57

Literature References

PubMed DOI Target Context # Activities
37736179 10.1021/acsmedchemlett.3c00098 RAW264.7 4
37473690 10.1016/j.ejmech.2023.115631 Nuclear receptor subfamily 1 group I member 3 2
28110817 10.1016/j.bmc.2016.09.042 Unchecked 1
34670362 10.1021/acs.jmedchem.1c00932 Tubulin 1
34670362 10.1021/acs.jmedchem.1c00932 Poly [ADP-ribose] polymerase 1 1
37473690 10.1016/j.ejmech.2023.115631 HepG2 1

Data from ChEMBL 36 via Core Engine