Compound Detail
CHEMBL149138
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Basic Information
| ChEMBL ID | CHEMBL149138 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WSMHUXDLXGUDEF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
450.5
MW (Da)
4.23
ALogP
7
HBA
4
HBD
132.7
PSA (Ų)
0.18
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 4.02
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glucagon receptor CHEMBL1985 | Ki | 4.02 | 4.02 | 95000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glucagon receptor | Ki | = | 95000.0 | nM | 4.02 | Binding affinity towards cloned human glucagon receptor in BHK cells. | 9857085 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9857085 | 10.1021/jm9810304 | Glucagon receptor | 1 |
Data from ChEMBL 36 via Core Engine