Compound Detail
CHEMBL1492498
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Basic Information
| ChEMBL ID | CHEMBL1492498 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YPGOVAKRQUAHIC-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
333.4
MW (Da)
3.80
ALogP
3
HBA
0
HBD
46.6
PSA (Ų)
0.85
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.02
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mucolipin-3 CHEMBL1293243 | EC50 | 6.02 | 6.005 | 950.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mucolipin-3 | EC50 | = | 950.0 | nM | 6.02 | PUBCHEM_BIOASSAY: Late stage results from the probe development effort to identi... | - |
| Mucolipin-3 | EC50 | = | 1030.0 | nM | 5.99 | PUBCHEM_BIOASSAY: Dose response cell-based high-throughput screening assay for a... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.6019/CHEMBL4495565 | SARS-CoV-2 | 2 |
| - | 10.6019/CHEMBL4495564 | Replicase polyprotein 1ab | 1 |
Data from ChEMBL 36 via Core Engine