Compound Detail
CHEMBL151672
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL151672 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CLVSDTWUASDNAN-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
318.4
MW (Da)
5.42
ALogP
1
HBA
1
HBD
37.3
PSA (Ų)
0.71
QED
1
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.45
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Retinoic acid receptor beta CHEMBL2008 | EC50 | 6.45 | 6.24 | 355.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Retinoic acid receptor beta | EC50 | = | 355.0 | nM | 6.45 | Transcriptional activation of retinoic acid receptor RAR beta | - |
| Retinoic acid receptor beta | EC50 | = | 930.0 | nM | 6.03 | Transcriptional activation of retinoic acid receptor RAR beta | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(95)00065-2 | Retinoic acid receptor beta | 2 |
| - | 10.1016/0960-894X(95)00065-2 | Retinoic acid receptor alpha | 1 |
| - | 10.1016/0960-894X(95)00065-2 | Retinoic acid receptor RXR-alpha | 1 |
| - | 10.1016/0960-894X(95)00065-2 | Mus musculus | 1 |
Data from ChEMBL 36 via Core Engine