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Compound Detail

CHEMBL1528028

PUTRESCINE DIHYDROCHLORIDE
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Basic Information

ChEMBL ID CHEMBL1528028
Name PUTRESCINE DIHYDROCHLORIDE
Phase Preclinical
Structure Type MOL
InChI Key XXWCODXIQWIHQN-UHFFFAOYSA-N
Parent Compound CHEMBL46257
Active Moiety CHEMBL46257
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
10
Publications
0
Known Names

Molecular Properties

88.2
MW (Da)
-0.32
ALogP
2
HBA
2
HBD
52.0
PSA (Ų)
0.46
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C4H14Cl2N2
MW 161.08
Aromatic Rings 0
Heavy Atoms 6
NP-Likeness 0.57

Activity Summary

Ki 1 meas.

Literature References

PubMed DOI Target Context # Activities
20925391 10.1021/jm1007648 Unchecked 2
- 10.6019/CHEMBL4495565 SARS-CoV-2 2
17417631 10.1038/nchembio873 Unchecked 1
23571415 10.1124/mol.112.084152 Solute carrier organic anion transporter family member 1B3 1
23571415 10.1124/mol.112.084152 Solute carrier organic anion transporter family member 1B1 1
24177358 10.1016/j.ejmech.2013.09.055 Huh-7 1
24177358 10.1016/j.ejmech.2013.09.055 Hepatitis C virus 1
926111 10.1021/jm00219a002 Unchecked 1
- 10.21203/rs.3.rs-23951/v1 SARS-CoV-2 1
- 10.6019/CHEMBL4495564 Replicase polyprotein 1ab 1

Data from ChEMBL 36 via Core Engine