Compound Detail
CHEMBL155075
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL155075 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QMGZEBDUIIJQFI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
342.4
MW (Da)
3.26
ALogP
5
HBA
2
HBD
79.5
PSA (Ų)
0.52
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.35
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic, AMPA CHEMBL2093871 | IC50 | 6.35 | 6.35 | 450.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic, AMPA | IC50 | = | 450.0 | nM | 6.35 | The compound was tested for its affinity for Ionotropic glutamate receptor AMPA ... | 10741560 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10741560 | 10.1016/s0960-894x(00)00054-8 | Glutamate receptor ionotropic, AMPA | 1 |
| 10741560 | 10.1016/s0960-894x(00)00054-8 | Glutamate NMDA receptor | 1 |
Data from ChEMBL 36 via Core Engine