Compound Detail
CHEMBL156451
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Basic Information
| ChEMBL ID | CHEMBL156451 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FCBATGXXEJIKGT-PKNBQFBNSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
253.3
MW (Da)
2.79
ALogP
3
HBA
1
HBD
46.9
PSA (Ų)
0.89
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Homo sapiens CHEMBL372 | IC50 | 5.8 | 5.345 | 1600.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Homo sapiens | IC50 | = | 1600.0 | nM | 5.8 | In vitro inhibition of ADP-induced aggregation of human PRP in the presence of p... | 1311763 |
| Homo sapiens | IC50 | = | 13000.0 | nM | 4.89 | Inhibition of ADP-induced aggregation of human PRP in the absence of pig aortal ... | 1311763 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1311763 | 10.1021/jm00082a002 | Homo sapiens | 3 |
Data from ChEMBL 36 via Core Engine