Compound Detail
CHEMBL158324
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL158324 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ICMFMHDOJYBSDI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
546.9
MW (Da)
6.12
ALogP
3
HBA
1
HBD
64.3
PSA (Ų)
0.18
QED
2
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein farnesyltransferase CHEMBL2094108 | IC50 | 6.64 | 6.64 | 230.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein farnesyltransferase | IC50 | = | 230.0 | nM | 6.64 | FPT inhibitory activity was determined by the ability to inhibit the transfer of... | 11844681 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11844681 | 10.1016/s0960-894x(01)00826-5 | Protein farnesyltransferase | 1 |
Data from ChEMBL 36 via Core Engine