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Compound Detail

CHEMBL16236

FLUORENE
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c1ccc2c(c1)Cc1ccccc1-2

Basic Information

ChEMBL ID CHEMBL16236
Name FLUORENE
Phase Preclinical
Structure Type MOL
InChI Key NIHNNTQXNPWCJQ-UHFFFAOYSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names

Molecular Properties

166.2
MW (Da)
3.26
ALogP
0
HBA
0
HBD
0.0
PSA (Ų)
0.48
QED
0
Ro5 Violations
0
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C13H10
MW 166.22
Aromatic Rings 2
Heavy Atoms 13
NP-Likeness -0.11

Activity Summary

EC50 1 meas. best 4.15

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Bovine viral diarrhea virus 1
CHEMBL612571
EC50 4.15 4.15 71000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
10866370 10.1016/s0960-894x(00)00172-4 No relevant target 1
18289862 10.1016/j.bmc.2008.01.052 Bovine viral diarrhea virus 1 1
18289862 10.1016/j.bmc.2008.01.052 ADMET 1
17629592 10.1016/j.ejmech.2007.05.007 No relevant target 1
27353886 10.1016/j.bmc.2016.06.036 Botulinum neurotoxin type E 1
32726747 10.1016/j.ejmech.2020.112635 MDA-MB-231 1

Data from ChEMBL 36 via Core Engine