Compound Detail
CHEMBL1628264
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Basic Information
| ChEMBL ID | CHEMBL1628264 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GSQYAWMREAXBHF-UOYQFSTFSA-N |
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
177.2
MW (Da)
-2.59
ALogP
5
HBA
5
HBD
106.9
PSA (Ų)
0.30
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 4 meas. best 5.12
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sucrase-isomaltase, intestinal CHEMBL2748 | IC50 | 5.12 | 5.12 | 7500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Sucrase-isomaltase, intestinal | IC50 | = | 7500.0 | nM | 5.12 | Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against p... | 3519969 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 3519969 | 10.1021/jm00156a023 | Maltase-glucoamylase | 1 |
| 3519969 | 10.1021/jm00156a023 | Sucrase-isomaltase, intestinal | 1 |
| 15380224 | 10.1016/j.bmcl.2004.07.091 | Unchecked | 1 |
| 15380224 | 10.1016/j.bmcl.2004.07.091 | Beta-galactosidase | 1 |
| 15380224 | 10.1016/j.bmcl.2004.07.091 | Cytosolic beta-glucosidase | 1 |
Data from ChEMBL 36 via Core Engine