Compound Detail
CHEMBL163269
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Basic Information
| ChEMBL ID | CHEMBL163269 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NHNFZSVAPDAFRV-UHFFFAOYSA-N |
| Parent Compound | CHEMBL1181306 |
| Active Moiety | CHEMBL1181306 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
454.6
MW (Da)
4.38
ALogP
5
HBA
3
HBD
101.0
PSA (Ų)
0.17
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein kinase C (PKC) CHEMBL2093867 | IC50 | 8.0 | 8.0 | 10.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein kinase C (PKC) | IC50 | = | 10.0 | nM | 8.0 | Inhibitory activity was evaluated against protein kinase C | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(94)00460-W | Protein kinase C (PKC) | 1 |
Data from ChEMBL 36 via Core Engine