Compound Detail
CHEMBL166426
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Basic Information
| ChEMBL ID | CHEMBL166426 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XYIDXIDDFVADKI-UHFFFAOYSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
330.1
MW (Da)
2.96
ALogP
4
HBA
3
HBD
107.7
PSA (Ų)
0.80
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas.
Ki 1 meas. best 5.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 CHEMBL330 | Ki | 5.15 | 5.15 | 7040.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Ki | = | 7040.0 | nM | 5.15 | Tested for the ability to displace [3H]glycine, by greater than 50%, from NMDA r... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(00)80096-7 | Glutamate receptor ionotropic, NMDA 1 | 1 |
| - | 10.1016/S0960-894X(00)80096-7 | Glutamate NMDA receptor | 1 |
Data from ChEMBL 36 via Core Engine