Compound Detail
CHEMBL166512
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Basic Information
| ChEMBL ID | CHEMBL166512 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UPGHVSRLCUIJPO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
268.3
MW (Da)
2.88
ALogP
3
HBA
1
HBD
67.5
PSA (Ų)
0.73
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 6.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Stimulator of interferon genes protein CHEMBL4523311 | Kd | 6.89 | 6.89 | 130.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Stimulator of interferon genes protein | Kd | = | 130.0 | nM | 6.89 | Agonist activity at mouse STING | 33773287 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2704025 | 10.1021/jm00124a012 | P388 | 2 |
| 2704025 | 10.1021/jm00124a012 | Unchecked | 1 |
| 2704025 | 10.1021/jm00124a012 | NON-PROTEIN TARGET | 1 |
| 33773287 | 10.1016/j.ejmech.2021.113356 | Stimulator of interferon genes protein | 1 |
Data from ChEMBL 36 via Core Engine