Compound Detail
CHEMBL1672276
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Basic Information
| ChEMBL ID | CHEMBL1672276 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PPAQOEIJUZVTEC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
262.7
MW (Da)
3.21
ALogP
3
HBA
0
HBD
36.7
PSA (Ų)
0.68
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 9.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Metabotropic glutamate receptor 5 CHEMBL2564 | Ki | 9.4 | 9.4 | 0.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Metabotropic glutamate receptor 5 | Ki | = | 0.4 | nM | 9.4 | Displacement of [3H]MPEP from mGluR5 in rat brain | 21207959 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21207959 | 10.1021/jm101430m | Metabotropic glutamate receptor 5 | 1 |
Data from ChEMBL 36 via Core Engine