Compound Detail
CHEMBL1673061
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Basic Information
| ChEMBL ID | CHEMBL1673061 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YYPWDEZHWMONKO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
233.2
MW (Da)
0.54
ALogP
4
HBA
4
HBD
113.0
PSA (Ų)
0.57
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.19
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | IC50 | 4.19 | 4.19 | 65000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | IC50 | = | 65000.0 | nM | 4.19 | Antimalarial activity against Plasmodium falciparum 3D7 infected in O-positive h... | 18458130 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18458130 | 10.1128/aac.01327-07 | Leucine aminopeptidase | 4 |
| 18458130 | 10.1128/aac.01327-07 | Plasmodium falciparum | 3 |
Data from ChEMBL 36 via Core Engine