Compound Detail
CHEMBL168177
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Basic Information
| ChEMBL ID | CHEMBL168177 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HYMWHCWYQWFBTD-WDEREUQCSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
273.4
MW (Da)
3.65
ALogP
3
HBA
1
HBD
24.0
PSA (Ų)
0.67
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus type 1 reverse transcriptase CHEMBL247 | EC50 | 6.1 | 6.1 | 790.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus type 1 reverse transcriptase | EC50 | = | 790.0 | nM | 6.1 | Effective concentration against HIV-1 reverse transcriptase | 10072684 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10072684 | 10.1021/jm980277y | Human immunodeficiency virus type 1 reverse transcriptase | 1 |
Data from ChEMBL 36 via Core Engine