Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL1688349

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
c1cnc(NCCc2ccncc2)c(-c2nnc(Nc3ccc4c(c3)OCCO4)o2)c1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL1688349
Phase Preclinical
Structure Type MOL
InChI Key GQWOYDSRMCLAPK-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

416.4
MW (Da)
3.70
ALogP
9
HBA
2
HBD
107.2
PSA (Ų)
0.47
QED
0
Ro5 Violations
7
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C22H20N6O3
MW 416.44
Aromatic Rings 4
Heavy Atoms 31
NP-Likeness -1.42

Literature References

PubMed DOI Target Context # Activities
24900236 10.1021/ml1001568 Vascular endothelial growth factor receptor 2 2
24900236 10.1021/ml1001568 Unchecked 1
24900236 10.1021/ml1001568 A-431 1

Data from ChEMBL 36 via Core Engine