Compound Detail
CHEMBL170056
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Basic Information
| ChEMBL ID | CHEMBL170056 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ITQVYWQVOUKFRB-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
289.2
MW (Da)
3.41
ALogP
2
HBA
0
HBD
16.1
PSA (Ų)
0.75
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 4.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate [NMDA] receptor CHEMBL2094124 | Ki | 4.82 | 4.82 | 15000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate [NMDA] receptor | Ki | = | 15000.0 | nM | 4.82 | Binding affinity against NMDA receptor by displacement of [3H]Ro-256981 | 12617901 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12617901 | 10.1016/s0960-894x(03)00007-6 | Glutamate [NMDA] receptor | 1 |
| 12617901 | 10.1016/s0960-894x(03)00007-6 | Adrenergic receptor alpha-1 | 1 |
| 12617901 | 10.1016/s0960-894x(03)00007-6 | Muscarinic acetylcholine receptor M1 | 1 |
| 12617901 | 10.1016/s0960-894x(03)00007-6 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine