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Compound Detail

CHEMBL17461

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C=C1C[C@@H]2C[C@@H]3C[C@@H](O)C[C@@H](O3)c3coc(n3)/C=C/C[C@H]3O[C@@H](/C(C)=C/c4coc(C[C@]5(O)C[C@H](OC)C[C@H](CO)O5)n4)[C@H](C)[C@@H](OC(=O)/C=C\C[C@@H](C1)O2)[C@H]3C

Basic Information

ChEMBL ID CHEMBL17461
Phase Preclinical
Structure Type MOL
InChI Key HMISUVTXHZLGGM-REUSRKTCSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

794.9
MW (Da)
5.57
ALogP
14
HBA
3
HBD
185.2
PSA (Ų)
0.24
QED
3
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C43H58N2O12
MW 794.94
Aromatic Rings 2
Heavy Atoms 57
NP-Likeness 1.85

Literature References

PubMed DOI Target Context # Activities
11354372 10.1016/s0960-894x(01)00191-3 NALM-6 1
11354372 10.1016/s0960-894x(01)00191-3 BT-20 1
11354372 10.1016/s0960-894x(01)00191-3 U373 MG 1
11354372 10.1016/s0960-894x(01)00191-3 Candida albicans 1
11354372 10.1016/s0960-894x(01)00191-3 Saccharomyces pastorianus 1

Data from ChEMBL 36 via Core Engine