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Compound Detail

CHEMBL1765882

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COC(=O)C1(O)C[C@@H](O)[C@@H](O)[C@H](OC(=O)/C=C\c2ccc(O)c(O)c2)C1

Basic Information

ChEMBL ID CHEMBL1765882
Phase Preclinical
Structure Type MOL
InChI Key MZNIJRAPCCELQX-RDSLDKPGSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

368.3
MW (Da)
-0.56
ALogP
9
HBA
5
HBD
153.8
PSA (Ų)
0.27
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C17H20O9
MW 368.34
Aromatic Rings 1
Heavy Atoms 26
NP-Likeness 2.13

Activity Summary

IC50 1 meas. best 4.73

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Radical scavenging activity
CHEMBL613712
IC50 4.73 4.73 18500.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
21341711 10.1021/np1007476 Radical scavenging activity 1

Data from ChEMBL 36 via Core Engine