Compound Detail
CHEMBL1765948
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1765948 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UHJQIXQKAMXPDZ-RSXGOPAZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
350.6
MW (Da)
8.35
ALogP
0
HBA
0
HBD
0.0
PSA (Ų)
0.29
QED
1
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Steroidogenic factor 1 CHEMBL4666 | EC50 | 6.6 | 6.6 | 251.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Steroidogenic factor 1 | EC50 | = | 251.19 | nM | 6.6 | Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-F... | 21391689 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21391689 | 10.1021/jm1014296 | Steroidogenic factor 1 | 2 |
| 21391689 | 10.1021/jm1014296 | Nuclear receptor subfamily 5 group A member 2 | 1 |
Data from ChEMBL 36 via Core Engine