Compound Detail
CHEMBL1773084
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Basic Information
| ChEMBL ID | CHEMBL1773084 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OVUQNWLJXWGRDU-UUILKARUSA-N |
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names
Molecular Properties
276.1
MW (Da)
1.76
ALogP
2
HBA
2
HBD
50.4
PSA (Ų)
0.49
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 4 meas. best 6.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatitis C virus CHEMBL379 | EC50 | 6.6 | 6.575 | 250.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatitis C virus | EC50 | = | 250.0 | nM | 6.6 | Antiviral activity against Hepatitis C virus infected in human Huh7ET cells asse... | 21376429 |
| Hepatitis C virus | EC50 | = | 280.0 | nM | 6.55 | Antiviral activity against Hepatitis C virus infected in human Huh7ET cells asse... | 21376429 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21376429 | 10.1016/j.ejmech.2011.02.014 | Unchecked | 8 |
| 21376429 | 10.1016/j.ejmech.2011.02.014 | Hepatitis C virus | 4 |
| 21376429 | 10.1016/j.ejmech.2011.02.014 | HFF | 4 |
| 21376429 | 10.1016/j.ejmech.2011.02.014 | Human alphaherpesvirus 3 | 2 |
| 21376429 | 10.1016/j.ejmech.2011.02.014 | ADMET | 2 |
| 21376429 | 10.1016/j.ejmech.2011.02.014 | Human betaherpesvirus 5 | 2 |
| 21376429 | 10.1016/j.ejmech.2011.02.014 | NON-PROTEIN TARGET | 2 |
| 21376429 | 10.1016/j.ejmech.2011.02.014 | Vaccinia virus | 2 |
Data from ChEMBL 36 via Core Engine