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Compound Detail

CHEMBL1774155

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CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCCCc4ccc(CCCCn5cc([C@@H](NC(=O)[C@@H]6CC[C@@H]7CCCC[C@H](NC(=O)[C@H](Cc8c[nH]c9ccccc89)NC(C)=O)C(=O)N76)c6ccccc6)nn5)cc4)nn3)N2C1=O

Basic Information

ChEMBL ID CHEMBL1774155
Phase Preclinical
Structure Type MOL
InChI Key KCRWCGKTNLNFIB-VUHFQLKMSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
4
Publications
0
Known Names

Molecular Properties

1407.7
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C80H94N16O8
MW 1407.74

Literature References

PubMed DOI Target Context # Activities
21462933 10.1021/jm101651b E3 ubiquitin-protein ligase XIAP 6
21462933 10.1021/jm101651b Baculoviral IAP repeat-containing protein 2 4
21462933 10.1021/jm101651b Baculoviral IAP repeat-containing protein 3 2
21462933 10.1021/jm101651b MDA-MB-231 1

Data from ChEMBL 36 via Core Engine