Compound Detail
CHEMBL1780109
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC[C@H]1C[C@@H](C(=O)NC[C@@H]2CCCO2)CN(Cc2nc(N3CCOCC3)oc2C)C1
Basic Information
| ChEMBL ID | CHEMBL1780109 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GSBNPYNSMWKTPP-OTWHNJEPSA-N |
0
Targets
0
Activities
0
Assay Types
2
PK Parameters
2
Publications
1
Known Names
Molecular Properties
420.6
MW (Da)
1.96
ALogP
7
HBA
1
HBD
80.1
PSA (Ų)
0.72
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Pharmacokinetic Data
| Parameter | Value | Units | Species |
|---|---|---|---|
| CL | 18.9 | mL.min-1.g-1 | Homo sapiens |
| T1/2 | 0.8617 | hr | Homo sapiens |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21459572 | 10.1016/j.bmcl.2011.03.022 | Liver microsomes | 2 |
| 21459572 | 10.1016/j.bmcl.2011.03.022 | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B | 1 |
Data from ChEMBL 36 via Core Engine