Compound Detail
CHEMBL178323
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Basic Information
| ChEMBL ID | CHEMBL178323 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VSHXTWPZEFJXNV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
400.5
MW (Da)
3.83
ALogP
3
HBA
0
HBD
40.6
PSA (Ų)
0.58
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.79
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M1 CHEMBL276 | Ki | 5.79 | 5.79 | 1620.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | Ki | = | 1620.0 | nM | 5.79 | Displacement of [3H]pirenzepine from muscarinic M1 receptor of rat cortex homoge... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(97)00143-1 | Muscarinic acetylcholine receptor M1 | 1 |
| - | 10.1016/S0960-894X(97)00143-1 | Muscarinic acetylcholine receptor M2 | 1 |
Data from ChEMBL 36 via Core Engine