Compound Detail
CHEMBL1789400
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Basic Information
| ChEMBL ID | CHEMBL1789400 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ODGCEQLVLXJUCC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
86.8
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.12
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sodium/iodide cotransporter CHEMBL2331047 | IC50 | 6.12 | 6.12 | 750.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Sodium/iodide cotransporter | IC50 | = | 750.0 | nM | 6.12 | Inhibition of sodium iodide symporter in rat FRTL5 cells assessed as decrease in... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 27283786 | 10.1016/j.bmc.2016.05.029 | Unchecked | 4 |
| 26853167 | 10.1016/j.bmcl.2016.01.072 | Unchecked | 2 |
| 26853167 | 10.1016/j.bmcl.2016.01.072 | Carbonic anhydrase 2 | 1 |
| 26853167 | 10.1016/j.bmcl.2016.01.072 | Carbonic anhydrase 1 | 1 |
| 27283786 | 10.1016/j.bmc.2016.05.029 | Carbonic anhydrase 2 | 1 |
| 27283786 | 10.1016/j.bmc.2016.05.029 | Carbonic anhydrase 1 | 1 |
Data from ChEMBL 36 via Core Engine