Compound Detail
CHEMBL1794797
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Basic Information
| ChEMBL ID | CHEMBL1794797 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HVRWFMCLXNLOCH-KVTDHHQDSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
147.2
MW (Da)
-1.94
ALogP
4
HBA
4
HBD
72.7
PSA (Ų)
0.35
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Alpha-mannosidase 2C1 CHEMBL2852 | IC50 | 6.22 | 6.22 | 600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Alpha-mannosidase 2C1 | IC50 | = | 600.0 | nM | 6.22 | Inhibitory activity against Mannosidase in jack bean (Canavalia ensiformis) | 2504921 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2504921 | 10.1021/jm00129a011 | Alpha-mannosidase 2C1 | 1 |
Data from ChEMBL 36 via Core Engine