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Compound Detail

CHEMBL1801949

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COc1cc(O)c2c(c1)/C=C/C[C@H](O)[C@H](O)[C@H](O)/C=C/C[C@H](C)OC2=O

Basic Information

ChEMBL ID CHEMBL1801949
Phase Preclinical
Structure Type MOL
InChI Key BPOLRDGTYHVUAY-OURSJTMWSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
10
Publications
0
Known Names

Molecular Properties

364.4
MW (Da)
1.39
ALogP
7
HBA
4
HBD
116.5
PSA (Ų)
0.44
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C19H24O7
MW 364.39
Aromatic Rings 1
Heavy Atoms 26
NP-Likeness 2.16

Literature References

PubMed DOI Target Context # Activities
21513293 10.1021/np200062x MCF7 1
21513293 10.1021/np200062x NCI-H460 1
21513293 10.1021/np200062x SF-268 1
21513293 10.1021/np200062x HT-29 1
21513293 10.1021/np200062x MDA-MB-435 1
21513293 10.1021/np200062x Transcription factor p65 1
21513293 10.1021/np200062x Escherichia coli 1
21513293 10.1021/np200062x Staphylococcus aureus 1
21513293 10.1021/np200062x Mycolicibacterium smegmatis 1
21513293 10.1021/np200062x Bacillus subtilis 1

Data from ChEMBL 36 via Core Engine