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Compound Detail

CHEMBL1807162

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C[C@H](NP(=O)(OC[C@H]1O[C@@H](n2cc(Cl)c(=O)[nH]c2=O)C(F)(F)[C@@H]1O)Oc1ccccc1)C(=O)OCc1ccccc1

Basic Information

ChEMBL ID CHEMBL1807162
Phase Preclinical
Structure Type MOL
InChI Key OATZJDFAZLVRED-ZMZPBXSZSA-N
0
Targets
4
Activities
1
Assay Types
0
PK Parameters
12
Publications
0
Known Names

Molecular Properties

615.9
MW (Da)
3.01
ALogP
10
HBA
3
HBD
158.2
PSA (Ų)
0.22
QED
1
Ro5 Violations
11
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C25H25ClF2N3O9P
MW 615.91
Aromatic Rings 3
Heavy Atoms 41
NP-Likeness 0.11

Activity Summary

IC50 4 meas.

Literature References

Data from ChEMBL 36 via Core Engine