Compound Detail
CHEMBL1813228
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1813228 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NTXNJVNYGXQNCQ-LURJTMIESA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
188.0
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 7.68 | 7.025 | 21.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 21.0 | nM | 7.68 | Inhibition of chymotrypsin-like activity of 20S proteasome using suc-LLVY-AMC as... | 21634429 |
| Unchecked | IC50 | = | 430.0 | nM | 6.37 | Inhibition of chymotrypsin-like activity of 20S proteasome using suc-LLVY-AMC as... | 21634429 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21634429 | 10.1021/jm200460q | Unchecked | 6 |
| 21634429 | 10.1021/jm200460q | ADMET | 3 |
| 21634429 | 10.1021/jm200460q | HEK293 | 2 |
Data from ChEMBL 36 via Core Engine