Compound Detail
CHEMBL1813239
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Basic Information
| ChEMBL ID | CHEMBL1813239 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SRRYMZZGXYMFGI-STQMWFEESA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
314.1
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 7.37
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 7.37 | 6.8233 | 43.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 43.0 | nM | 7.37 | Inhibition of chymotrypsin-like activity of 20S proteasome using suc-LLVY-AMC as... | 21634429 |
| Unchecked | IC50 | = | 100.0 | nM | 7.0 | Inhibition of chymotrypsin-like activity of 20S proteasome using suc-LLVY-AMC as... | 21634429 |
| Unchecked | IC50 | = | 790.0 | nM | 6.1 | Inhibition of intracellular chymotrypsin-like activity of 20S proteasome in huma... | 21634429 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21634429 | 10.1021/jm200460q | Unchecked | 6 |
| 21634429 | 10.1021/jm200460q | ADMET | 1 |
Data from ChEMBL 36 via Core Engine