Compound Detail
CHEMBL181760
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL181760 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FNZFELZOBRBQJY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
478.3
MW (Da)
6.19
ALogP
6
HBA
1
HBD
62.3
PSA (Ų)
0.44
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| GABA-A receptor; anion channel CHEMBL2093872 | IC50 | 6.3 | 6.3 | 500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| GABA-A receptor; anion channel | IC50 | = | 500.0 | nM | 6.3 | In vitro insecticidal activity as inhibition of [3H]EBOB binding to Gamma-aminob... | 15341958 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15341958 | 10.1016/j.bmcl.2004.07.033 | GABA-A receptor; anion channel | 2 |
Data from ChEMBL 36 via Core Engine