Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL1818133

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CCN(CC)Cc1cc(Nc2c3ccc(Cl)cc3nc3c(OC)ccc(Cl)c23)ccc1O
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL1818133
Phase Preclinical
Structure Type MOL
InChI Key TZWDXFWBOHBUEC-UHFFFAOYSA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

470.4
MW (Da)
6.99
ALogP
5
HBA
2
HBD
57.6
PSA (Ų)
0.23
QED
1
Ro5 Violations
7
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C25H25Cl2N3O2
MW 470.40
Aromatic Rings 4
Heavy Atoms 32
NP-Likeness -0.98

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
21831641 10.1016/j.bmc.2011.07.020 Unchecked 2
21831641 10.1016/j.bmc.2011.07.020 Escherichia coli 2
21831641 10.1016/j.bmc.2011.07.020 Staphylococcus aureus 2

Data from ChEMBL 36 via Core Engine