Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL1818437

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
OC[C@@H]1NCC[C@@H](O)[C@@H]1O
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL1818437
Phase Preclinical
Structure Type MOL
InChI Key YZNNBIPIQWYLDM-KVQBGUIXSA-N
0
Targets
2
Activities
1
Assay Types
0
PK Parameters
10
Publications
0
Known Names

Molecular Properties

147.2
MW (Da)
-1.94
ALogP
4
HBA
4
HBD
72.7
PSA (Ų)
0.35
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C6H13NO3
MW 147.17
Aromatic Rings 0
Heavy Atoms 10
NP-Likeness 2.96

Activity Summary

IC50 2 meas.

Literature References

PubMed DOI Target Context # Activities
21546253 10.1016/j.bmc.2011.04.011 Unchecked 8
21546253 10.1016/j.bmc.2011.04.011 Sucrase-isomaltase, intestinal 2
24900342 10.1021/ml200050s Ceramide glucosyltransferase 2
21546253 10.1016/j.bmc.2011.04.011 Glucosylceramidase 1
21546253 10.1016/j.bmc.2011.04.011 Lysosomal acid glucosylceramidase 1
21546253 10.1016/j.bmc.2011.04.011 Beta-galactosidase 1
21546253 10.1016/j.bmc.2011.04.011 Tissue alpha-L-fucosidase 1
21546253 10.1016/j.bmc.2011.04.011 Lactase/phlorizin hydrolase 1
24900342 10.1021/ml200050s Unchecked 1
24900342 10.1021/ml200050s Beta-glucosidase 1

Data from ChEMBL 36 via Core Engine