Compound Detail
CHEMBL1823932
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1823932 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MJZVDDVMMUIMCG-UZYOAWRESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
295.4
MW (Da)
2.29
ALogP
4
HBA
1
HBD
72.5
PSA (Ų)
0.29
QED
0
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 8.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transcriptional activator protein LasR CHEMBL1075207 | EC50 | 8.0 | 8.0 | 10.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transcriptional activator protein LasR | EC50 | = | 10.0 | nM | 8.0 | Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Es... | 20669927 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20669927 | 10.1021/jm901742e | Transcriptional activator protein LasR | 1 |
| 24592914 | 10.1021/jm500215s | Unchecked | 1 |
| 24592914 | 10.1021/jm500215s | Staphylococcus aureus | 1 |
Data from ChEMBL 36 via Core Engine