Compound Detail
CHEMBL1830694
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Basic Information
| ChEMBL ID | CHEMBL1830694 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GNTYTRMYRRTNNR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
257.3
MW (Da)
2.98
ALogP
5
HBA
2
HBD
66.5
PSA (Ų)
0.76
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Metabotropic glutamate receptor 4 CHEMBL2736 | EC50 | 7.89 | 7.89 | 13.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Metabotropic glutamate receptor 4 | EC50 | = | 13.0 | nM | 7.89 | Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells as... | 21688779 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21688779 | 10.1021/jm200290z | Metabotropic glutamate receptor 4 | 2 |
Data from ChEMBL 36 via Core Engine