Compound Detail
CHEMBL187024
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Basic Information
| ChEMBL ID | CHEMBL187024 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OWXLNPQDZKOGNB-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
317.4
MW (Da)
2.67
ALogP
3
HBA
2
HBD
65.2
PSA (Ų)
0.73
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.03
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein kinase C beta type CHEMBL3045 | IC50 | 6.03 | 6.03 | 939.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein kinase C beta type | IC50 | = | 939.0 | nM | 6.03 | Inhibitory concentration against recombinant human Protein kinase C beta 2 | 15380221 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15380221 | 10.1016/j.bmcl.2004.07.061 | Protein kinase C beta type | 1 |
Data from ChEMBL 36 via Core Engine