Compound Detail
CHEMBL1893588
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Basic Information
| ChEMBL ID | CHEMBL1893588 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VBQNSZQZRAGRIX-QNEBEIHSSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
320.5
MW (Da)
5.43
ALogP
2
HBA
1
HBD
49.8
PSA (Ų)
0.26
QED
1
Ro5 Violations
14
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 4 CHEMBL6126 | EC50 | 6.82 | 6.82 | 150.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 4 | EC50 | = | 150.0 | nM | 6.82 | Agonist activity at mouse TRPV4 | 32063431 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 32063431 | 10.1016/j.bmcl.2020.127022 | Transient receptor potential cation channel subfamily V member 4 | 1 |
Data from ChEMBL 36 via Core Engine