Compound Detail
CHEMBL191628
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Basic Information
| ChEMBL ID | CHEMBL191628 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XZXUAZNGFQLVGU-FPYGCLRLSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
297.3
MW (Da)
2.82
ALogP
4
HBA
2
HBD
67.8
PSA (Ų)
0.85
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.4 | 4.4 | 39810.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 39810.72 | nM | 4.4 | Inhibition of rat human chimera TRPV1 channel expressed in CHO cells | 17948977 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15634002 | 10.1021/jm049485i | Transient receptor potential cation channel subfamily V member 1 | 2 |
| 17948977 | 10.1021/jm070261k | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine