Compound Detail
CHEMBL1928586
SERINOLAMIDE A Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1928586 |
| Name | SERINOLAMIDE A |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CJAVPRNATZCNLN-NBRGKURFSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
383.6
MW (Da)
5.49
ALogP
3
HBA
1
HBD
49.8
PSA (Ų)
0.24
QED
1
Ro5 Violations
19
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.64
Ki 1 meas. best 5.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cannabinoid receptor 1 CHEMBL218 | Ki | 5.89 | 5.89 | 1300.0 | 1 |
| Cannabinoid receptor 1 CHEMBL218 | IC50 | 5.64 | 5.64 | 2300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cannabinoid receptor 1 | Ki | = | 1300.0 | nM | 5.89 | Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in HEK... | 21999614 |
| Cannabinoid receptor 1 | IC50 | = | 2300.0 | nM | 5.64 | Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in HEK... | 21999614 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21999614 | 10.1021/np200610t | Cannabinoid receptor 1 | 2 |
| 21999614 | 10.1021/np200610t | NCI-H460 | 2 |
| 21999614 | 10.1021/np200610t | Cannabinoid receptor 2 | 1 |
| 21999614 | 10.1021/np200610t | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine