Compound Detail
CHEMBL1934121
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Basic Information
| ChEMBL ID | CHEMBL1934121 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CXNTZUFNPDUZFN-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
451.6
MW (Da)
5.93
ALogP
3
HBA
1
HBD
37.3
PSA (Ų)
0.42
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 10.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Melanin-concentrating hormone receptor 2 CHEMBL5038 | IC50 | 10.0 | 10.0 | 0.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Melanin-concentrating hormone receptor 2 | IC50 | = | 0.1 | nM | 10.0 | Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as i... | 22123324 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22123324 | 10.1016/j.bmcl.2011.10.125 | Melanin-concentrating hormone receptor 2 | 1 |
Data from ChEMBL 36 via Core Engine