Compound Detail
CHEMBL1951280
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Basic Information
| ChEMBL ID | CHEMBL1951280 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GPACLUXKWVKLOA-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
435.6
MW (Da)
1.67
ALogP
8
HBA
2
HBD
95.4
PSA (Ų)
0.65
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycylpeptide N-tetradecanoyltransferase CHEMBL3988596 | IC50 | 6.0 | 6.0 | 1000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glycylpeptide N-tetradecanoyltransferase | IC50 | = | 1000.0 | nM | 6.0 | Enzyme Inhibition Assay: Measurements were performed using a modification of the... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22148754 | 10.1021/jm201091t | Unchecked | 1 |
| 22148754 | 10.1021/jm201091t | Glycylpeptide N-tetradecanoyltransferase 1 | 1 |
Data from ChEMBL 36 via Core Engine