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Compound Detail

CHEMBL195441

BUTYLBENZYL
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Basic Information

ChEMBL ID CHEMBL195441
Name BUTYLBENZYL
Phase Preclinical
Structure Type MOL
InChI Key OCKPCBLVNKHBMX-UHFFFAOYSA-N
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

134.2
MW (Da)
3.03
ALogP
0
HBA
0
HBD
0.0
PSA (Ų)
0.60
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C10H14
MW 134.22
Aromatic Rings 1
Heavy Atoms 10
NP-Likeness -0.20

Activity Summary

IC50 1 meas.
Kd 1 meas. best 4.85

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Endolysin
CHEMBL5206
Kd 4.85 4.85 14000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Endolysin Kd = 14000.0 nM 4.85 Dissociation constant against T4 lysozyme mutant L99A 15916423

Literature References

PubMed DOI Target Context # Activities
15916423 10.1021/jm0491187 Endolysin 1
15916432 10.1021/jm0489713 Cytochrome P450 1A2 1
17629592 10.1016/j.ejmech.2007.05.007 No relevant target 1

Data from ChEMBL 36 via Core Engine