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Compound Detail

CHEMBL1957447

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N.N.O=c1ccn([C@@H]2O[C@H](CCP(=O)(O)O)[C@@H](O)[C@H]2Cl)c(=O)[nH]1

Basic Information

ChEMBL ID CHEMBL1957447
Phase Preclinical
Structure Type MOL
InChI Key YWXXWVSEJVWOID-BAZBJWKESA-N
Parent Compound CHEMBL1963537
Active Moiety CHEMBL1963537
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

340.7
MW (Da)
-1.03
ALogP
6
HBA
4
HBD
141.8
PSA (Ų)
0.41
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C10H20ClN4O7P
MW 374.72
Aromatic Rings 1
Heavy Atoms 21
NP-Likeness 0.93

Literature References

PubMed DOI Target Context # Activities
22386981 10.1016/j.bmc.2012.02.012 P2Y purinoceptor 2 2
22386981 10.1016/j.bmc.2012.02.012 P2Y purinoceptor 6 1
22386981 10.1016/j.bmc.2012.02.012 P2Y purinoceptor 4 1

Data from ChEMBL 36 via Core Engine