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Compound Detail

CHEMBL1966557

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O=c1ccn([C@@H]2C=C(CO)[C@@H](O)[C@H]2O)c(=O)[nH]1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL1966557
Phase Preclinical
Structure Type MOL
InChI Key FCWVOJUKQSHZIV-VDAHYXPESA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names

Molecular Properties

240.2
MW (Da)
-2.27
ALogP
6
HBA
4
HBD
115.5
PSA (Ų)
0.44
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C10H12N2O5
MW 240.22
Aromatic Rings 1
Heavy Atoms 17
NP-Likeness 1.21

Activity Summary

Ki 1 meas.

Literature References

PubMed DOI Target Context # Activities
6094806 10.1021/jm00378a002 L1210 3
6094806 10.1021/jm00378a002 Uridine-cytidine kinase 1 2
6094806 10.1021/jm00378a002 FYVE, RhoGEF and PH domain-containing protein 1 1
11689085 10.1021/jm010256v Human immunodeficiency virus 1 1
11689085 10.1021/jm010256v West Nile virus 1
11689085 10.1021/jm010256v ADMET 1
11689085 10.1021/jm010256v Vero 1
11689085 10.1021/jm010256v CCRF-CEM 1

Data from ChEMBL 36 via Core Engine